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Jane Metcalfe

Founder & CEO

Jane Metcalfe is the CEO and founder of proto.life, a weekly newsletter, website, book, and events company tracking how digital tools and an engineering mindset are transforming human biology. She is chair of the Human Immunome Project, a global consortium of researchers, industry, and NGOs using emerging tools of artificial intelligence to build working models of the human immunome. She is also co-chair of the Futures Council of the Focused Ultrasound Foundation and advises various startups. Prior to that, Jane made chocolate on a pier in San Francisco as the President of TCHO Chocolate. But Jane is probably best known as the cofounder and former president of Wired Magazine / Wired Ventures, Inc., the legendary media company that chronicled the digital revolution as it was happening from a front row seat. Under Jane’s and her cofounder Louis Rossetto’s leadership, the magazine grew to an internationally renowned brand and a diversified media company featuring U.S., U.K., and Japanese editions, a book division, a television show and HotWired, the first original online content backed by Fortune 500 advertising, inventing the advertising banner along the way (which they discussed but didn’t patent). There was also HotBot, at the time the fastest search engine in the world.