At Concerto Biosciences, we are obsessed with microbes. We dream of a healthier world where microbial ecology enables advanced medicines and environmentally-conscious agricultural practices. To unlock microbial ecology, Concerto uses a novel screening technology from MIT to construct and observe millions of microbial cocultures in parallel—each its own tiny universe of possibilities. Our technology generates a totally new type of microbiome data that allows us to identify groups of microbes that perform beneficial functions. We call these groups “ensembles”. We are currently in the preclinical stage for our first product, an ensemble to treat eczema—a chronic, irritating, and psychologically stressful skin disease that affects over two hundred million people. Our goal is to discover the first-ever treatment that provides totally safe, sustained relief for eczema patients. Concerto will go on to develop a multitude of ensembles that solve the world’s greatest challenges in human health, food production, and bioremediation.
The Concerto team is our most important ensemble. We believe the best human ensembles, much like microbial ensembles, are diverse—composed of individuals with different backgrounds, cultures, genders, and beliefs. We are committed to building a company where you belong and where your voice is heard.
As a Scientist – Fermentation, your primary goal will be to develop a fermentation process for the manufacturing of Concerto’s first live biotherapeutic product (LBP), “Ensemble No.2” (ENS-002), as a Phase I-ready drug product. To this end, you will help set up a new, bench-scale process development process (including laboratory equipment, protocols, and establishment of best practices); you will also potentially guide future developments of phase-appropriate GMP manufacturing capabilities. You will develop a bioprocess for manufacturing each of several strains comprising the ENS-002 drug substance (DS); work closely with Analytical and Quality efforts to develop and validate release assays; provide technical oversight for technology transfer either internally or to a CDMO; and serve as the fermentation subject matter expert for CDMO management, product disposition, and regulatory submissions.
This role will benefit from experience in traditional cGMP manufacturing of LBPs as well as willingness to experiment and innovate on CMC pipelines for LBP manufacturing. We don’t expect you to have experience performing all of the responsibilities listed below. Indeed, just as you help Concerto grow, we hope to contribute to your intellectual and professional growth. You’ll have the opportunity to gain new skills by working with our world-class team, and you’ll also have the opportunity to advance within the company by taking on higher responsibility roles. As an early member of Concerto’s expanding team, you’ll play a critical role in developing Concerto’s culture and translating our core values into practice.
Please send your cover letter and resume or CV to Dr. Bernardo Cervantes at email@example.com.
COVID-19 Policy: All on-site employees must be fully vaccinated against COVID-19, and all new hires for on-site roles must be fully vaccinated by the time they start employment. During the interview process, you will be asked to confirm that, if hired, you can satisfy this express condition of employment. At present, an individual is deemed “fully vaccinated” when that person has received, at least 14 days prior, either the second dose in a two-dose COVID-19 vaccine series (e.g., Pfizer or Moderna) or a single-dose COVID-19 vaccine (e.g., Johnson & Johnson). The Company will make reasonable accommodations under applicable law for qualified individuals to enable them to perform the essential functions of the job, unless doing so would create an undue hardship for the Company.