What we're looking for

We are seeking an exceptional computational biologist to join our R&D team and establish an in-silico modelling platform to accelerate the development of a high performing strain producing isoprenoids at industrial scale.

We post education and experience requirements along with a salary range for transparency and to allow candidates to have a sense of our expectations.If it doesn’t match perfectly, don’t hesitate to apply, we are flexible!

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Responsibilities

• Model new metabolisms at the genome scale and new-to-nature synthetic pathways in microbial strainsAs an extension, model the fermentor environment for industrial production

• Integrate important quantitative metabolomics data in order to model, predict impact and suggest targets for optimising metabolic fluxes in order to increase production of isoprenoids

• Work in a "design-build-test-learn” cycle with the wet lab teams to test pathways and develop solutions to overcome challenges

Qualifications

Hard skills

• Proficiency in at least one data-related programming language (Python, R, SQL)

• Ability to build data pipelines to integrate multiple data sources

• Experience in modelling metabolic and biological processes:

  • Flux balance analysis, metabolic flux analysis

  • Genome sequence analysis including comparative genomics, genome assembly, alignment, gene structure and gene function annotation methods and tools

  • Enzyme kinetics, chemical data

• Ability to interface with the wet lab team

• Bonus: experience in CO2 fixation/reduction and C1/C2 metabolism

• Bonus: experience modelling industrial fermentation

• Bonus: professional experience in startup or industry

Soft skills

• Great team player

• Autonomy, action-oriented mindset, ability to take initiatives

• Optimism and adaptability

• Clear communication in English

• Excellent organisational skills

• Creativity and scientific curiosity

Benefits

• Employee Stock Options (BSPCE)

• Health insurance (Alan) 100% covered

• Lunch voucher of 12€/day ( 7€/day paid by the company), 2 team lunches per months

• 500€ per year for all your mobility needs (bike, subway, car-sharing…)

• Individual training budget for skills development

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