Research Associate - Mammalian Synthetic Biology
Our mission is to enable pharmaceutical and biotechnology companies to bring more cell and gene therapies to patients, by dramatically increasing the efficiency of viral vector production and reducing the cost of manufacturing. 64x Bio was founded by world renowned scientists and experts in gene therapy from Harvard and the Wyss Institute. Our rapidly growing and cross disciplinary team consists of creative bioengineers and synthetic biologists working alongside data scientists to create cutting-edge solutions to problems in gene therapy.
Responsibilities
Support Scientists with cell line development including cloning, characterization, and cell banking.
Generate and validate cell lines using tools such as CRISPR, lentivirus, recombinases, and other methods.
Cell culture maintenance with adherent and suspension mammalian cell lines.
Transient transfection via physical and chemical methods.
Molecular biology support including cloning, PCR, sequencing (Sanger, NGS), ddPCR, and qPCR.
Contribute to the writing and maintenance of SOPs.
Communicate and present experimental and project progress to Synthetic Biology and other groups at 64x Bio.
Collaborate with Operations and other teams at 64x to secure experimental resources to complete experiments in a timely manner.
Influence and support 64x Bio’s overall direction as a company as well as its evolving needs and company culture, as needed.
About You
BA or MA in synthetic biology, molecular biology, bioengineering, cell biology or related field.
4+ years of wet lab experience in a mammalian biology context across academia and industry.
Experience with mammalian cell culture.
Working knowledge of genetic engineering methods applicable to mammalian cells.
Stable cell line generation experience.
Demonstrated ability to identify, troubleshoot, and resolve problems quickly.
Ability to reprioritize throughout the day and week as new needs arise in a dynamic and fast-paced environment.
Strong organizational skills and ability to systematically and effectively multitask/advance many projects simultaneously.
Excellent communication skills, with the ability to effectively convey complex technical information to a wide range of internal teams.
Expertise in Google Suite and Mac OSX as well as proficiency in Windows systems.
Preferred
Experience with flow cytometry.
Prior industry experience.
