Senior Bioinformatics Developer

Full Time
San Carlos, California, United States
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Elegen is blazing a path towards a biology-based economy with a highly innovative approach to DNA synthesis that delivers an industry leading length of 7kb in 7 business days with a 99.999% per base accuracy. Our multidisciplinary team of best-in-class biologists, chemists, hardware, and software engineers apply cutting-edge technologies and methods to solve critical bottlenecks in synthetic biology workflows to help our customers in pharma, biotech, agbio, and biomanufacturing streamline their work and realize the full potential of programmable biology.

This is an opportunity to join a rapidly growing company at an early stage and impact the development of its products, markets, processes, people, and culture.

This is a rare and exciting opportunity for a software engineer looking to take the next step in their career at a uniquely innovative, rapidly moving, high impact start-up. As a Senior Bioinformatics Developer, you will be responsible for supporting and improving our bioinformatics pipelines and LIMS in a fast-paced production environment.  You will work directly with wet-bench scientists to improve our technology, and with bioinformaticians to improve our NGS algorithms.

Essential Responsibilities:

  • Work with scientists to automate lab protocols and analyze results.
  • Collaborate with lab operations teams to support production lab environments.
  • Troubleshoot and resolve operational issues in a timely manner, including on-call rotations.
  • Optimize, update and maintain various production data processing and bioinformatic analysis pipelines.
  • Develop important bioinformatics tools, algorithms, and analysis methods to complement Elegen’s novel synthetic DNA production platform.
  • Build, optimize, automate, and maintain various processing or analysis pipelines.
  • Provide computational support and data-based guidance to the R&D and operations teams.
  • Design and build front-end analysis interfaces for internal use.
  • Help design and build databases and server networks for internal and external applications.

Essential Qualifications and Experience:

  • BS or MS in computer science, bioinformatics, computational biology, genomics, or a related field.
  • 5-7 years of industry experience.
  • Proficiency in Python programming.
  • Python web development - Flask, SQLAlchemy.
  • Cloud computing, especially AWS (Batch, Lambda).
  • Next-Generation Sequencing (NGS) analysis.
  • Workflow management systems - Cromwell/WDL/Nextflow.
  • Familiarity with software development best practices, including version control using GitHub, testing and tracking (Jira), continuous integration and deployment (Jenkins).
  • Demonstrated ability to collaborate and communicate effectively in interdisciplinary teams.

Preferred Qualifications and Experience:

  • Experience with DevOps (AWS).
  • Experience with Lab Information Management Systems.
  • Familiarity with machine learning, statistics, and predictive modeling.
  • Familiarity with molecular biology or synthetic biology approaches and methods.
  • Project Management Skills.

Salary and Benefits:

The annual base salary compensation for this role, if based in California is: $160,000 - $185,000. Compensation may be different in other locations.  Final compensation also includes bonus, equity and benefits.   Specific offer packages are determined by multiple factors, including candidate skill, experience, expertise, and location.

✓ Healthcare    ✓ Dental    ✓ Vision    ✓ Learning Allowance

✓ 401K    ✓ Flexible PTO   ✓ Short Term Disability    ✓ Fitness Allowance

About The Company:

Founded and led by Dr. Matthew Hill and located in San Carlos, CA, Elegen is well-capitalized by top life science investors, including Andreessen Horowitz, 8VC, and KdT. The company is advised and staffed by leading biotechnology scientists and entrepreneurs, including Dr. Marc Unger, inventor of the Nanoflex™ valve, and former CSO of Fluidigm. Dr. Hill has a PhD from Stanford and a proven track record of advancing innovative technologies from invention to commercial success. Over eight years in his previous role as VP of R&D at a leading molecular diagnostics company, he co-invented and launched five precision molecular diagnostic products, including a best-in-class noninvasive prenatal test used by millions. These products earn more than $350 million per year in revenue and enabled an IPO.

Elegen is an Equal Opportunity Employer.

Elegen provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.  All applicants have rights under the following Federal Employment Laws:

Remote Position
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